Most commonly this puja is performed to assist in the recovery of illness or an operation. It is also done to achieve higher rebirth for the deceased.
This puja is especially helpful for those who are experiencing physical or mental illness or those who have recently passed away.
The Medicine Buddha Puja can be performed extensively, with the requests to Medicine Buddhas done seven times to each of the Buddhas. Additional prayers are said for the dedication of the merit.
By creating extensive merit through the performance of the puja, Medicine Buddha puja is also very helpful to bring success in all activities, for example, work-related.