Synergy of Meditation and Psilocybin - Insights from Brain Connectivity Maps
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Synergy of Meditation and Psilocybin – Insights from Brain Connectivity Maps

A recent published in Scientific Reports explores the potential synergy between and , shedding light on their combined effects on brain connectivity.

Open monitoring meditation, characterized by broad awareness of experience without or judgment, was combined with psilocybin to enhance insightfulness in experienced meditators.

Psilocybin, a psychedelic compound found in certain mushrooms, is known for its profound effects on and cognition.

By analyzing functional magnetic resonance imaging (fMRI) data using topological data analysis, researchers found that psilocybin significantly altered the brain’s connectivity patterns, particularly during meditation.

Participants who received psilocybin showed increased connectivity between brain regions associated with open monitoring meditation, suggesting enhanced transition between different states of .

Notably, psilocybin-induced positive derealization, a perception of reality as more meaningful, was strongly linked to perceived insightfulness.

The findings suggest that psilocybin may amplify the depth and of meditation by facilitating a deeper disengagement from ordinary consciousness and promoting heightened awareness.

While the study offers promising insights, limitations include the small sample size and focus on experienced meditators, warranting further research to generalize findings and explore the broader of psychedelics and meditation.


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